GSDMB

Across TCGA cell cohorts, GSDMB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,577 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GSDMB-associated GO terms across cancer lineages are Taurine biosynthetic process, Alkanesulfonate biosynthetic process, and Sperm motility. Each is linked with GSDMB in more than 11 cancer types. Because this analysis shows association rather than direction, both GSDMB-to-partner and partner-to-GSDMB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Taurine biosynthetic process grouped by GSDMB-low versus GSDMB-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GSDMB→partner) and Y-score (partner→GSDMB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Taurine biosynthetic process →	+0.891	+1.144	.003	<.001	3	12
OVARY	Alkanesulfonate biosynthetic process →	+0.891	+1.144	.003	<.001	3	12
OESOPHAGUS	Sperm motility →	-0.133	-2.442	<.001	<.001	3	12
OESOPHAGUS	Flagellated sperm motility →	-0.133	-2.442	<.001	<.001	3	12
OVARY	Intracellular sphingolipid homeostasis →	+0.179	+1.231	<.001	<.001	3	11
LUNG_SCLC	tRNA 5'-end processing →	-0.092	-1.374	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,577 associations by consensus.

Taurine biosynthetic process by GSDMB expression — OVARY

Explore this box plot interactively →