GSDMA

Across TCGA patient cohorts, GSDMA RNA expression is significantly associated with the protein abundance of many other proteins, with 11,234 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GSDMA-associated proteins across cancer lineages are MYO5A, TUBA4A, and CLIP1. Each is linked with GSDMA in more than 3 cancer types. Because this analysis shows association rather than direction, both GSDMA-to-partner and partner-to-GSDMA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSDMA versus MYO5A in UCEC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSDMA→partner) and Y-score (partner→GSDMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYO5A →	+0.347	+0.815	<.001	<.001	3	4
HNSC	TUBA4A →	+0.861	+2.405	<.001	<.001	3	4
HNSC	CLIP1 →	+0.416	+1.858	<.001	<.001	3	4
HNSC	EHBP1L1 →	+0.354	+1.726	<.001	.001	3	4
GBM	SART3 →	-0.246	-0.850	<.001	<.001	3	4
OV	MPP1 →	+0.408	+0.634	.009	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,234 associations by consensus.

GSDMA vs MYO5A — UCEC

Explore this scatter interactively →