Across TCGA pan-cancer cohorts, GSAP Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GSAP data layer compared with 25 for mass-spec protein and 4 for mass-spec protein.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher GSAP Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated GSAP expression acts as an unfavorable survival marker, although some lineages such as SKCM and STAD show a favorable association.
ACC, SKCM, and HNSC are the cancer types where GSAP Mutation most reproducibly stratifies survival.
Mutation survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.