Across TCGA patient cohorts, GRXCR2 mutation is significantly associated with the RNA expression of many other genes, with 1,102 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRXCR2-associated genes across cancer lineages are AZI2, POC1A, and DTYMK. Each is linked with GRXCR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRXCR2-to-partner and partner-to-GRXCR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRXCR2→partner) and Y-score (partner→GRXCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	AZI2 →	+0.618	+3.362	.001	.005	3	2
UCEC	POC1A →	+0.683	+3.475	.004	.002	3	2
UCEC	DTYMK →	+0.574	+3.483	.003	.002	3	2
UCEC	COQ2 →	+0.546	+3.818	.002	<.001	3	2
UCEC	MAP4 →	+0.404	+3.202	.009	.009	3	2
SKCM	DNAJC25 →	+0.611	+2.019	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,102 associations by consensus.

Exploration

GRXCR2 survival (RNA) · tumor vs normal (RNA) · all GRXCR2 data types