Across TCGA cell cohorts, GRXCR2 RNA expression is significantly associated with the go_rna of many other GO terms, with 760 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible GRXCR2-associated GO terms across cancer lineages are Regulation of protein localization to membrane, Membrane protein proteolysis, and Glycine biosynthetic process. Each is linked with GRXCR2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRXCR2-to-partner and partner-to-GRXCR2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRXCR2→partner) and Y-score (partner→GRXCR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of protein localization to membrane →	+0.046	+0.041	<.001	.009	3	5
BREAST	Membrane protein proteolysis →	+0.071	+0.021	.002	.004	3	5
BLOOD_Myeloma	Glycine biosynthetic process →	+0.131	+0.022	.003	.004	3	4
UPPER_AERODIGESTIVE_TRACT	Positive regulation of inclusion body assembly →	+0.163	+0.121	.001	.008	3	4
LUNG_NSCLC_LUAD	Tight junction organization →	+0.071	+0.035	<.001	<.001	3	4
LUNG_NSCLC_LUAD	Regulation of ruffle assembly →	+0.133	+0.039	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 760 associations by consensus.

Exploration

GRXCR2 survival (RNA) · tumor vs normal (RNA) · all GRXCR2 data types