GRXCR1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GRXCR1 mutation is significantly associated with the RNA expression of many other genes, with 978 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRXCR1-associated genes across cancer lineages are CABS1, TUSC2, and RN7SL386P. Each is linked with GRXCR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GRXCR1-to-partner and partner-to-GRXCR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRXCR1→partner) and Y-score (partner→GRXCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCCABS1 →+0.041+3.225<.001.00833
SKCMTUSC2 →+0.236+1.883.006.00233
BRCARN7SL386P →+0.105+4.912<.001.00332
HNSCOR9I1 →+0.069+3.813.001.00732
CESCRNU6-770P →+0.545+4.304<.001.00332
HNSCSPTLC1P2 →+0.318+3.974.007.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 978 associations by consensus.

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