Across TCGA cell cohorts, GRXCR1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GRXCR1-associated genes across cancer lineages are REELD1, NEU2, and BEND2. Each is linked with GRXCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRXCR1-to-partner and partner-to-GRXCR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRXCR1→partner) and Y-score (partner→GRXCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	REELD1 →	+0.114	+3.556	.002	.001	3	2
LARGE_INTESTINE	NEU2 →	+0.025	+2.791	<.001	.005	3	1
LARGE_INTESTINE	BEND2 →	+0.013	+3.240	<.001	.004	3	1
LARGE_INTESTINE	MOG →	+0.091	+3.639	.002	<.001	3	1
LARGE_INTESTINE	TECRL →	+0.011	+3.240	<.001	.004	3	1
BLOOD_Leukemia	ACTRT2 →	+0.112	+4.922	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

GRXCR1 survival (RNA) · tumor vs normal (RNA) · all GRXCR1 data types