GRSF1

Across TCGA patient cohorts, GRSF1 mutation is significantly associated with the RNA expression of many other genes, with 1,622 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRSF1-associated genes across cancer lineages are RNA5SP436, LCEP1, and RNU6ATAC30P. Each is linked with GRSF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRSF1-to-partner and partner-to-GRSF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by GRSF1-low versus GRSF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRSF1→partner) and Y-score (partner→GRSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP436 →	+0.219	+2.615	<.001	.004	3	2
LUAD	LCEP1 →	+0.079	+7.930	<.001	.008	3	2
LIHC	RNU6ATAC30P →	+0.282	+5.268	<.001	.006	3	2
LIHC	RPL26P3 →	+0.110	+5.033	<.001	.009	3	2
HNSC	NF1P6 →	+0.271	+3.639	<.001	.006	3	2
SKCM	OR10G9 →	+0.039	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,622 associations by consensus.

RNA5SP436 by GRSF1 expression — UCEC

Explore this box plot interactively →