GRPR

Across TCGA patient cohorts, GRPR protein abundance is significantly associated with the RNA expression of many other genes, with 773 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GRPR-associated genes across cancer lineages are KCTD17, CTSG, and PYGL. Each is linked with GRPR in more than 1 cancer types. Because this analysis shows association rather than direction, both GRPR-to-partner and partner-to-GRPR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRPR versus KCTD17 in BRCA, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRPR→partner) and Y-score (partner→GRPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KCTD17 →	+1.564	+0.991	.006	.004	3	1
BRCA	CTSG →	+2.282	+0.821	.003	.004	3	1
BRCA	PYGL →	+1.617	+1.122	.002	<.001	3	1
BRCA	RIMS4 →	+4.824	+1.108	<.001	<.001	3	1
BRCA	SPEF1 →	+2.098	+0.944	<.001	.005	3	1
BRCA	MROH8 →	+0.907	+0.977	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 773 associations by consensus.

GRPR vs KCTD17 — BRCA

Explore this scatter interactively →