GRPEL2P1

Across TCGA pan-cancer cohorts, GRPEL2P1 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated GRPEL2P1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher GRPEL2P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GRPEL2P1 expression acts as an unfavorable survival marker.

STAD, THCA, and SKCM are the cancer types where GRPEL2P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	All	0.444	0.742	.001	108	view →
THCA	OS	Tertile	II,III,IV	0.045	0.874	<.001	93	view →
SKCM	OS	Tertile	II,III,IV	0.417	0.752	<.001	75	view →
BLCA	OS	Tertile	IV	0.074	0.599	<.001	72	view →
LUSC	DFS	Tertile	III,IV	0.010	0.754	<.001	72	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	36	view →
UCS	OS	Tertile	All	0.185	0.686	.034	18	view →
LAML	DFS	Tertile	All	0.028	0.583	.001	18	view →
SARC	OS	Tertile	All	0.342	0.737	.010	9	view →
UCEC	OS	Tertile	All	0.890	0.927	.048	6	view →
ESCA	OS	Tertile	All	0.511	0.701	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

GRPEL2P1–STAD (DFS)

Open the STAD breakdown →