GRPEL1

Across TCGA patient cohorts, GRPEL1 RNA expression is significantly associated with the mutation status of many other genes, with 12,235 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRPEL1-associated genes across cancer lineages are ADGRV1, COL11A1, and LAMA5. Each is linked with GRPEL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GRPEL1-to-partner and partner-to-GRPEL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ADGRV1 grouped by GRPEL1-low versus GRPEL1-high in SARC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRPEL1→partner) and Y-score (partner→GRPEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	ADGRV1 →	+3.237	+0.464	.008	.003	3	6
STAD	COL11A1 →	+2.182	+0.359	.001	<.001	3	6
HNSC	LAMA5 →	+3.330	+0.425	.005	.002	3	5
LIHC	OBSCN →	+1.797	+0.233	.006	.002	3	5
STAD	DNAH3 →	+2.597	+0.369	<.001	.001	3	5
CESC	TCHH →	+3.489	+0.560	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,235 associations by consensus.

ADGRV1 by GRPEL1 expression — SARC

Explore this box plot interactively →