GRPEL1

Across TCGA patient cohorts, GRPEL1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,023 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GRPEL1-associated genes across cancer lineages are JAM3, LHFPL6, and HERC1. Each is linked with GRPEL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GRPEL1-to-partner and partner-to-GRPEL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRPEL1 versus JAM3 in OV, with a Pearson correlation of -0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRPEL1→partner) and Y-score (partner→GRPEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	JAM3 →	-0.777	-0.485	<.001	<.001	3	8
OV	LHFPL6 →	-0.782	-0.328	<.001	.004	3	8
OV	HERC1 →	-0.835	-0.463	<.001	<.001	3	7
BRCA	HMCN1 →	-1.287	-0.510	<.001	<.001	3	7
OV	CXCL12 →	-1.606	-0.523	.001	.002	3	7
UCEC	CNRIP1 →	-0.678	-0.551	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,023 associations by consensus.

GRPEL1 vs JAM3 — OV

Explore this scatter interactively →