GRPEL1

Across TCGA cell cohorts, GRPEL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,014 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GRPEL1-associated GO terms across cancer lineages are Ribosomal small subunit biogenesis, 'de novo' IMP biosynthetic process, and rRNA processing. Each is linked with GRPEL1 in more than 15 cancer types. Because this analysis shows association rather than direction, both GRPEL1-to-partner and partner-to-GRPEL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal small subunit biogenesis grouped by GRPEL1-low versus GRPEL1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRPEL1→partner) and Y-score (partner→GRPEL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Ribosomal small subunit biogenesis →	+0.083	+0.571	.003	.009	3	16
LIVER	'de novo' IMP biosynthetic process →	+0.140	+0.867	.004	<.001	3	15
LIVER	rRNA processing →	+0.099	+0.708	<.001	<.001	3	15
LUNG_SCLC	Ribosome biogenesis →	+0.111	+1.005	<.001	<.001	3	15
SOFT_TISSUE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.084	+0.507	.004	.005	3	15
LIVER	rRNA metabolic process →	+0.089	+0.646	.001	<.001	2	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,014 associations by consensus.

Ribosomal small subunit biogenesis by GRPEL1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →