GRN

Across TCGA patient cohorts, GRN RNA expression is significantly associated with the protein abundance of many other proteins, with 14,220 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRN-associated proteins across cancer lineages are APOBR, STAT2, and CTSS. Each is linked with GRN in more than 6 cancer types. Because this analysis shows association rather than direction, both GRN-to-partner and partner-to-GRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRN versus APOBR in BRCA, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRN→partner) and Y-score (partner→GRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APOBR →	+0.595	+0.887	<.001	<.001	3	7
GBM	STAT2 →	+0.589	+0.758	<.001	<.001	3	6
GBM	CTSS →	+0.743	+0.792	<.001	<.001	3	6
PDAC	TYROBP →	+0.767	+0.323	<.001	<.001	3	6
GBM	SKAP2 →	+0.726	+0.696	<.001	<.001	3	5
OV	SPN →	+0.786	+1.231	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,220 associations by consensus.

GRN vs APOBR — BRCA

Explore this scatter interactively →