Across TCGA patient cohorts, GRM7 protein abundance is significantly associated with the RNA expression of many other genes, with 5,994 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRM7-associated genes across cancer lineages are DPP4, PFN1, and TLNRD1. Each is linked with GRM7 in more than 2 cancer types. Because this analysis shows association rather than direction, both GRM7-to-partner and partner-to-GRM7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM7→partner) and Y-score (partner→GRM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DPP4 →	+2.318	+0.920	<.001	<.001	3	3
UCEC	PFN1 →	-0.620	-1.321	.004	.003	3	2
LUAD	TLNRD1 →	-0.480	-0.736	.003	<.001	3	2
UCEC	ADD3 →	+0.724	+0.911	.009	.004	3	2
UCEC	C16orf89 →	+3.757	+1.680	.001	<.001	3	2
LUAD	MOCS2 →	+0.477	+0.762	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,994 associations by consensus.

Exploration

GRM7 survival (RNA) · tumor vs normal (RNA) · all GRM7 data types