Q-omics provides the consensus-scored GRM7-AS3 profile across patient tissues and cancer cell-line models. GRM7-AS3 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, GRM7-AS3 is differentially expressed in 6, with the highest sampling consensus in KIRP. Additionally, GRM7-AS3 RNA expression shows 9,405 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight THCA, KIRP, and THYM as cancer lineages where GRM7-AS3 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GRM7-AS3 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GRM7-AS3 survival associations across molecular data types. GRM7-AS3 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GRM7-AS3 RNA expression–survival associations across cancer types. High GRM7-AS3 expression shows unfavorable associations in THCA, KIRP, ACC, LIHC and CHOL, but favorable associations in COAD. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for GRM7-AS3 RNA expression.
This table summarizes GRM7-AS3 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KIRP for RNA.
This table ranks reproducible tumor–normal expression differences for GRM7-AS3. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GRM7-AS3 shows lower tumor expression in KIRP and KICH and higher tumor expression in LUSC, LIHC, LUAD and STAD. The KIRP box plot shows higher GRM7-AS3 RNA expression in normal versus tumor tissue (log2 FC = −0.070, t-test p < 0.001).
This table shows molecular features associated with GRM7-AS3 in patient tissues and cancer cell lines. In patient samples, GRM7-AS3 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
