GRM6

Across TCGA patient cohorts, GRM6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,222 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRM6-associated proteins across cancer lineages are RAB23, RAI14, and PURA. Each is linked with GRM6 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRM6-to-partner and partner-to-GRM6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRM6 versus RAB23 in PDAC, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM6→partner) and Y-score (partner→GRM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RAB23 →	+0.328	+0.162	.002	.001	3	5
HNSC	RAI14 →	+0.275	+0.212	<.001	.001	3	5
UCEC	PURA →	+0.322	+0.289	<.001	.008	3	4
CCRCC	C1orf198 →	+0.563	+0.263	<.001	<.001	3	4
CCRCC	MPRIP →	+0.340	+0.236	<.001	.001	3	4
BRCA	GALNT7 →	-0.525	-0.209	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,222 associations by consensus.

GRM6 vs RAB23 — PDAC

Explore this scatter interactively →