GRM6

Across TCGA cell cohorts, GRM6 RNA expression is significantly associated with the go_rna of many other GO terms, with 508 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GRM6-associated GO terms across cancer lineages are Nuclear transport, Regulatory ncRNA-mediated gene silencing, and RNA localization. Each is linked with GRM6 in more than 5 cancer types. Because this analysis shows association rather than direction, both GRM6-to-partner and partner-to-GRM6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear transport grouped by GRM6-low versus GRM6-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM6→partner) and Y-score (partner→GRM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear transport →	+0.056	+0.254	.003	.009	3	6
LUNG_NSCLC_LUAD	Regulatory ncRNA-mediated gene silencing →	+0.038	+0.133	<.001	.009	3	6
BONE	RNA localization →	+0.082	+0.167	.001	.004	3	5
BONE	Nucleocytoplasmic transport →	+0.055	+0.255	.005	.009	2	6
BONE	tRNA transcription →	+0.093	+0.234	.005	.003	3	5
OVARY	Protein-DNA complex organization →	+0.029	+0.065	.002	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 508 associations by consensus.

Nuclear transport by GRM6 expression — BONE

Explore this box plot interactively →