GRM5

Across TCGA patient cohorts, GRM5 protein abundance is significantly associated with the RNA expression of many other genes, with 3,816 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRM5-associated genes across cancer lineages are PRODH, GRK3, and LGALS1. Each is linked with GRM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRM5-to-partner and partner-to-GRM5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRM5 versus PRODH in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM5→partner) and Y-score (partner→GRM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+0.928	+0.551	.001	.001	3	1
GBM	GRK3 →	+0.484	+0.556	<.001	<.001	3	1
GBM	LGALS1 →	-0.580	-0.519	.002	<.001	3	1
GBM	SOX10 →	+1.901	+0.577	<.001	<.001	3	1
GBM	SLC16A8 →	+0.465	+0.444	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.003	+0.577	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,816 associations by consensus.

GRM5 vs PRODH — GBM

Explore this scatter interactively →