GRM4

Across TCGA patient cohorts, GRM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,395 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRM4-associated proteins across cancer lineages are DLGAP4_T915, FBP2, and UBXN6. Each is linked with GRM4 in more than 3 cancer types. Because this analysis shows association rather than direction, both GRM4-to-partner and partner-to-GRM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRM4 versus DLGAP4_T915 in LSCC, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM4→partner) and Y-score (partner→GRM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DLGAP4_T915 →	+0.772	+0.615	<.001	<.001	3	4
UCEC	FBP2 →	-1.089	-0.447	<.001	<.001	3	4
LUAD	UBXN6 →	-0.194	-0.225	.003	.002	3	3
OV	STIM1 →	-0.471	-0.418	<.001	.002	3	3
GBM	STXBP1 →	+1.257	+0.364	<.001	<.001	3	3
LSCC	STMN1 →	+0.526	+0.650	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,395 associations by consensus.

GRM4 vs DLGAP4_T915 — LSCC

Explore this scatter interactively →