Across TCGA patient cohorts, GRM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,242 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRM3-associated proteins across cancer lineages are STXBP1, NEO1, and EEF1G. Each is linked with GRM3 in more than 3 cancer types. Because this analysis shows association rather than direction, both GRM3-to-partner and partner-to-GRM3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM3→partner) and Y-score (partner→GRM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	STXBP1 →	+0.912	+1.533	<.001	<.001	3	4
GBM	NEO1 →	+0.504	+1.311	<.001	<.001	3	4
BRCA	EEF1G →	-0.244	-0.087	<.001	<.001	3	4
BRCA	EPM2AIP1 →	+0.502	+0.096	<.001	.001	3	4
LSCC	FOSL2_S120 →	-0.661	-0.258	<.001	<.001	3	4
LSCC	MYEF2 →	+0.824	+0.304	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,242 associations by consensus.

Exploration

GRM3 survival (RNA) · tumor vs normal (RNA) · all GRM3 data types