Across TCGA cell cohorts, GRM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,073 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GRM3-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Positive regulation of DNA repair, and Epigenetic regulation of gene expression. Each is linked with GRM3 in more than 6 cancer types. Because this analysis shows association rather than direction, both GRM3-to-partner and partner-to-GRM3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM3→partner) and Y-score (partner→GRM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	Positive regulation of organelle assembly →	+0.040	+0.025	<.001	.002	3	6
URINARY_TRACT	Positive regulation of DNA repair →	+0.039	+0.030	.004	.008	2	7
STOMACH	Epigenetic regulation of gene expression →	+0.080	+0.138	<.001	.009	3	6
SOFT_TISSUE	Positive regulation of double-strand break repair →	+0.057	+0.087	.001	.009	2	6
BLOOD_Leukemia	Negative regulation of syncytium formation by plasma membrane fusion →	+0.051	+0.026	<.001	.005	2	6
LARGE_INTESTINE	Positive regulation of double-strand break repair via homologous recombination →	+0.034	+0.028	.005	.009	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,073 associations by consensus.

Exploration

GRM3 survival (RNA) · tumor vs normal (RNA) · all GRM3 data types