GRM2

Across TCGA patient cohorts, GRM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,051 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRM2-associated proteins across cancer lineages are DBN1, MALSU1, and C1S. Each is linked with GRM2 in more than 3 cancer types. Because this analysis shows association rather than direction, both GRM2-to-partner and partner-to-GRM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRM2 versus DBN1 in BRCA, with a Pearson correlation of 0.17.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM2→partner) and Y-score (partner→GRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DBN1 →	+0.378	+0.154	.003	.007	3	4
LUAD	MALSU1 →	-0.450	-0.201	<.001	.004	3	4
BRCA	C1S →	+0.791	+0.216	<.001	.002	3	4
GBM	CACNB3_S152 →	+0.408	+0.679	<.001	<.001	3	3
COAD	AEBP1 →	+0.733	+0.111	<.001	<.001	3	3
COAD	EIF1 →	-0.214	-0.099	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,051 associations by consensus.

GRM2 vs DBN1 — BRCA

Explore this scatter interactively →