GRM2

Across TCGA patient cohorts, GRM2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,111 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRM2-associated genes across cancer lineages are SNRPD3, PRODH, and SOX10. Each is linked with GRM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRM2-to-partner and partner-to-GRM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRM2 versus SNRPD3 in GBM, with a Pearson correlation of 0.26.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM2→partner) and Y-score (partner→GRM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.293	+0.486	.009	.003	3	1
GBM	PRODH →	+0.798	+0.443	<.001	.001	3	1
GBM	SOX10 →	+1.222	+0.605	<.001	<.001	3	1
GBM	SLC16A8 →	+0.532	+0.478	<.001	<.001	3	1
GBM	SEPTIN3 →	+0.961	+0.716	<.001	<.001	3	1
GBM	RASL10A →	+0.783	+0.597	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,111 associations by consensus.

GRM2 vs SNRPD3 — GBM

Explore this scatter interactively →