Across TCGA patient cohorts, GRK6 protein abundance is significantly associated with the RNA expression of many other genes, with 15,461 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRK6-associated genes across cancer lineages are SAMSN1, SLA, and CLEC4E. Each is linked with GRK6 in more than 7 cancer types. Because this analysis shows association rather than direction, both GRK6-to-partner and partner-to-GRK6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK6→partner) and Y-score (partner→GRK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAMSN1 →	+0.961	+0.240	<.001	<.001	3	8
HNSC	SLA →	+1.108	+0.334	<.001	<.001	3	8
COAD	CLEC4E →	+1.399	+0.380	<.001	<.001	3	8
LSCC	FPR2 →	+1.172	+0.371	<.001	<.001	3	8
HNSC	LILRA5 →	+0.956	+0.252	<.001	<.001	3	8
LSCC	SELL →	+1.279	+0.440	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,461 associations by consensus.

Exploration

GRK6 survival (RNA) · tumor vs normal (RNA) · all GRK6 data types