Across TCGA cell cohorts, GRK6 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,531 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible GRK6-associated GO terms across cancer lineages are Protein depolymerization, Positive regulation of mitotic cell cycle phase transition, and Protein localization to chromatin. Each is linked with GRK6 in more than 13 cancer types. Because this analysis shows association rather than direction, both GRK6-to-partner and partner-to-GRK6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK6→partner) and Y-score (partner→GRK6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Protein depolymerization →	+0.141	+1.551	<.001	<.001	3	14
CNS	Positive regulation of mitotic cell cycle phase transition →	+0.087	+0.851	<.001	<.001	3	13
PANCREAS	Protein localization to chromatin →	+0.112	+1.071	<.001	<.001	3	12
PANCREAS	Negative regulation of cell cycle phase transition →	+0.062	+1.111	<.001	<.001	3	12
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.194	+1.135	.007	<.001	3	12
SOFT_TISSUE	Chromosome condensation →	+0.175	+0.955	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,531 associations by consensus.

Exploration

GRK6 survival (RNA) · tumor vs normal (RNA) · all GRK6 data types