Across TCGA patient cohorts, GRK5-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,537 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GRK5-IT1-associated proteins across cancer lineages are HSPH1, JPT2, and SNRK_S362. Each is linked with GRK5-IT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GRK5-IT1-to-partner and partner-to-GRK5-IT1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK5-IT1→partner) and Y-score (partner→GRK5-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HSPH1 →	-0.487	-0.679	.003	.005	3	5
LSCC	JPT2 →	-0.310	-0.740	<.001	<.001	3	5
PDAC	SNRK_S362 →	+0.452	+0.610	.001	<.001	3	5
HNSC	GIMAP8 →	+0.461	+0.622	<.001	.006	2	6
CCRCC	PLVAP →	+0.668	+0.804	<.001	<.001	3	4
OV	SERPINA1 →	+0.559	+0.200	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,537 associations by consensus.

Exploration

GRK5-IT1 survival (RNA) · tumor vs normal (RNA) · all GRK5-IT1 data types