Across TCGA patient cohorts, GRK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,896 significant associations in total. THCA shows the largest number of these associations.

The most reproducible GRK1-associated GO terms across cancer lineages are Nucleotide-excision repair, Obsolete histone methylation, and Obsolete histone H3-K4 methylation. Each is linked with GRK1 in more than 25 cancer types. Because this analysis shows association rather than direction, both GRK1-to-partner and partner-to-GRK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRK1→partner) and Y-score (partner→GRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Nucleotide-excision repair →	+0.074	+0.965	.001	.002	3	25
SCLC	Obsolete histone methylation →	+0.130	+1.149	.005	.006	1	26
THYM	Obsolete histone H3-K4 methylation →	+0.095	+0.448	<.001	<.001	3	23
STAD	Base-excision repair →	+0.057	+0.123	<.001	<.001	3	23
UCS	Obsolete positive regulation of histone methylation →	+0.108	+0.517	<.001	<.001	2	24
SCLC	Obsolete histone modification →	+0.091	+1.510	.002	<.001	1	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,896 associations by consensus.

Exploration

GRK1 survival (RNA) · tumor vs normal (RNA) · all GRK1 data types