GRIPAP1

Across TCGA cell cohorts, GRIPAP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,185 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GRIPAP1-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Positive regulation of intracellular estrogen receptor signaling pathway, and Regulation of mRNA splicing, via spliceosome. Each is linked with GRIPAP1 in more than 17 cancer types. Because this analysis shows association rather than direction, both GRIPAP1-to-partner and partner-to-GRIPAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by GRIPAP1-low versus GRIPAP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIPAP1→partner) and Y-score (partner→GRIPAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.160	+1.125	<.001	<.001	3	18
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.169	+0.806	<.001	<.001	3	18
BLOOD_Lymphoma	Regulation of mRNA splicing, via spliceosome →	+0.104	+0.967	<.001	<.001	3	17
OESOPHAGUS	mRNA splice site recognition →	+0.134	+0.673	<.001	.002	3	17
LUNG_SCLC	Post-Golgi vesicle-mediated transport →	+0.107	+1.074	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.071	+1.004	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,185 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by GRIPAP1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →