GRIP2

Across TCGA cell cohorts, GRIP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 978 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GRIP2-associated GO terms across cancer lineages are Positive regulation of telomerase RNA localization to Cajal body, Negative regulation of calcium ion export across plasma membrane, and Regulation of nucleotide-excision repair. Each is linked with GRIP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both GRIP2-to-partner and partner-to-GRIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of telomerase RNA localization to Cajal body grouped by GRIP2-low versus GRIP2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIP2→partner) and Y-score (partner→GRIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of telomerase RNA localization to Cajal body →	+0.110	+1.084	<.001	.004	3	7
OESOPHAGUS	Negative regulation of calcium ion export across plasma membrane →	+0.077	+0.679	<.001	.003	3	7
KIDNEY	Regulation of nucleotide-excision repair →	+0.118	+0.287	<.001	.002	3	6
UPPER_AERODIGESTIVE_TRACT	Protein-DNA complex organization →	+0.046	+0.362	.003	.005	3	5
STOMACH	Regulation of double-strand break repair →	+0.052	+0.622	<.001	.009	3	5
STOMACH	Negative regulation of translational initiation →	+0.066	+0.807	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 978 associations by consensus.

Positive regulation of telomerase RNA localization to Cajal body by GRIP2 expression — STOMACH

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