GRINA

Across TCGA patient cohorts, GRINA RNA expression is significantly associated with the protein abundance of many other proteins, with 10,181 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GRINA-associated proteins across cancer lineages are PYCR3, SCRIB, and FAM83H_S1068. Each is linked with GRINA in more than 6 cancer types. Because this analysis shows association rather than direction, both GRINA-to-partner and partner-to-GRINA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRINA versus PYCR3 in BRCA, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRINA→partner) and Y-score (partner→GRINA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PYCR3 →	+0.525	+0.942	<.001	<.001	3	7
LSCC	SCRIB →	+0.299	+0.365	<.001	.006	3	4
LSCC	FAM83H_S1068 →	+0.590	+0.461	.003	<.001	3	4
LSCC	FAM83H_S516 →	+0.644	+0.360	.001	<.001	3	4
LSCC	FAM83H_S523 →	+0.667	+0.398	.002	.002	3	4
PDAC	PNPLA2_S428 →	+0.672	+0.345	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,181 associations by consensus.

GRINA vs PYCR3 — BRCA

Explore this scatter interactively →