GRIN3B

Across TCGA patient cohorts, GRIN3B protein abundance is significantly associated with the RNA expression of many other genes, with 1,624 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIN3B-associated genes across cancer lineages are PRODH, GRK3, and SEPTIN3. Each is linked with GRIN3B in more than 1 cancer types. Because this analysis shows association rather than direction, both GRIN3B-to-partner and partner-to-GRIN3B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIN3B versus PRODH in GBM, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN3B→partner) and Y-score (partner→GRIN3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	-0.984	-0.861	.004	.005	3	1
GBM	GRK3 →	-0.560	-1.156	.003	.004	3	1
GBM	SEPTIN3 →	-1.653	-1.139	.003	.001	3	1
GBM	PYGL →	+1.174	+1.372	.003	<.001	3	1
GBM	GALNT16 →	-1.126	-1.195	.001	.003	3	1
GBM	MYLK2 →	-0.685	-1.171	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,624 associations by consensus.

GRIN3B vs PRODH — GBM

Explore this scatter interactively →