GRIN3B

Across TCGA cell cohorts, GRIN3B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,082 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GRIN3B-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Response to starvation, and Regulation of cytoplasmic pattern recognition receptor signaling pathway. Each is linked with GRIN3B in more than 10 cancer types. Because this analysis shows association rather than direction, both GRIN3B-to-partner and partner-to-GRIN3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by GRIN3B-low versus GRIN3B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN3B→partner) and Y-score (partner→GRIN3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.113	+0.481	.001	.002	3	11
LUNG_NSCLC_LUAD	Response to starvation →	+0.054	+0.553	<.001	.004	3	10
LUNG_NSCLC_LUAD	Regulation of cytoplasmic pattern recognition receptor signaling pathway →	+0.049	+0.533	<.001	<.001	3	9
OESOPHAGUS	Negative regulation of calcium ion export across plasma membrane →	+0.061	+0.452	.004	.005	3	8
BLOOD_Leukemia	Negative regulation of DNA-templated transcription initiation →	+0.128	+0.183	<.001	<.001	3	8
BLOOD_Leukemia	Glycerophospholipid biosynthetic process →	+0.032	+0.174	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,082 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by GRIN3B expression — OESOPHAGUS

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