Across TCGA patient cohorts, GRIN3A mutation is significantly associated with the RNA expression of many other genes, with 3,723 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRIN3A-associated genes across cancer lineages are CDKN3, NDUFA12, and NDUFA6. Each is linked with GRIN3A in more than 3 cancer types. Because this analysis shows association rather than direction, both GRIN3A-to-partner and partner-to-GRIN3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN3A→partner) and Y-score (partner→GRIN3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDKN3 →	+0.461	+1.386	.003	.004	3	4
LUAD	NDUFA12 →	+0.311	+2.173	.001	.008	3	4
UCEC	NDUFA6 →	+0.420	+1.760	<.001	<.001	3	4
UCEC	TSPY26P →	-0.615	-2.459	<.001	<.001	3	4
UCEC	EIF4EBP3 →	-0.469	-2.360	.001	<.001	3	4
UCEC	UHRF1 →	+0.675	+1.439	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,723 associations by consensus.

Exploration

GRIN3A survival (RNA) · tumor vs normal (RNA) · all GRIN3A data types