Across TCGA patient cohorts, GRIN3A mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRIN3A-associated genes across cancer lineages are PCNA, ASNS, and ATM. Each is linked with GRIN3A in more than 2 cancer types. Because this analysis shows association rather than direction, both GRIN3A-to-partner and partner-to-GRIN3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN3A→partner) and Y-score (partner→GRIN3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.216	+1.925	<.001	.004	3	3
COAD	ASNS →	+0.724	+2.459	<.001	.018	3	3
UCEC	ATM →	-0.377	-1.295	.004	.010	3	3
UCEC	Cyclin-B1 →	+0.591	+2.584	<.001	<.001	3	3
SKCM	p53 →	+0.129	+1.289	.006	.016	3	3
COAD	TSC1 →	-0.432	-2.321	<.001	.032	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Exploration

GRIN3A survival (RNA) · tumor vs normal (RNA) · all GRIN3A data types