GRIN1

Across TCGA patient cohorts, GRIN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,550 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIN1-associated proteins across cancer lineages are ARFIP2, ELAPOR1, and MRC2. Each is linked with GRIN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRIN1-to-partner and partner-to-GRIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIN1 versus ARFIP2 in UCEC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN1→partner) and Y-score (partner→GRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARFIP2 →	+0.352	+0.681	<.001	<.001	3	5
BRCA	ELAPOR1 →	+0.924	+0.677	<.001	<.001	3	4
LSCC	MRC2 →	-0.532	-0.273	<.001	<.001	3	4
GBM	NPDC1_S229 →	+1.579	+1.676	<.001	<.001	3	4
GBM	ZYX →	-0.331	-1.244	<.001	<.001	3	3
GBM	PPP2R5E →	+0.250	+1.275	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,550 associations by consensus.

GRIN1 vs ARFIP2 — UCEC

Explore this scatter interactively →