GRIN1

Across TCGA patient cohorts, GRIN1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,087 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIN1-associated genes across cancer lineages are SNRPD3, PRODH, and GRK3. Each is linked with GRIN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRIN1-to-partner and partner-to-GRIN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIN1 versus SNRPD3 in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN1→partner) and Y-score (partner→GRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.385	+0.461	<.001	.006	3	1
GBM	PRODH →	+0.724	+0.651	<.001	<.001	3	1
GBM	GRK3 →	+0.530	+0.607	<.001	<.001	3	1
GBM	SEZ6L →	+1.438	+0.482	<.001	<.001	3	1
GBM	SOX10 →	+1.513	+0.589	<.001	<.001	3	1
GBM	SLC16A8 →	+0.436	+0.495	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,087 associations by consensus.

GRIN1 vs SNRPD3 — GBM

Explore this scatter interactively →