GRIN1

Across TCGA cell cohorts, GRIN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,671 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GRIN1-associated GO terms across cancer lineages are Positive regulation of voltage-gated potassium channel activity, Vesicle docking, and Positive regulation of calcium ion transport into cytosol. Each is linked with GRIN1 in more than 7 cancer types. Because this analysis shows association rather than direction, both GRIN1-to-partner and partner-to-GRIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of voltage-gated potassium channel activity grouped by GRIN1-low versus GRIN1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN1→partner) and Y-score (partner→GRIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Positive regulation of voltage-gated potassium channel activity →	+1.475	+1.700	<.001	<.001	3	8
LUNG_SCLC	Vesicle docking →	+0.094	+1.780	<.001	<.001	3	8
BONE	Positive regulation of calcium ion transport into cytosol →	-0.388	-1.189	<.001	<.001	3	8
SOFT_TISSUE	Muscle organ development →	-0.090	-0.569	<.001	.008	3	7
URINARY_TRACT	Negative regulation of RNA splicing →	+0.097	+0.506	.003	.001	3	7
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.082	+0.517	.003	.007	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,671 associations by consensus.

Positive regulation of voltage-gated potassium channel activity by GRIN1 expression — BREAST

Explore this box plot interactively →