GRIK5

Across TCGA cell cohorts, GRIK5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,115 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GRIK5-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, RNA catabolic process, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with GRIK5 in more than 14 cancer types. Because this analysis shows association rather than direction, both GRIK5-to-partner and partner-to-GRIK5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by GRIK5-low versus GRIK5-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIK5→partner) and Y-score (partner→GRIK5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Negative regulation of myoblast fusion →	+0.115	+1.216	<.001	.006	3	15
BONE	RNA catabolic process →	+0.091	+2.186	<.001	<.001	3	15
PANCREAS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.110	+0.433	<.001	.001	3	14
KIDNEY	Regulation of syncytium formation by plasma membrane fusion →	+0.112	+1.064	<.001	.005	3	14
BONE	Nucleic acid catabolic process →	+0.065	+2.153	<.001	<.001	3	13
BONE	Regulation of myoblast fusion →	+0.104	+2.674	<.001	<.001	2	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,115 associations by consensus.

Negative regulation of myoblast fusion by GRIK5 expression — KIDNEY

Explore this box plot interactively →