GRIK1

Across TCGA cell cohorts, GRIK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 527 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GRIK1-associated GO terms across cancer lineages are Ear morphogenesis, Muscle adaptation, and Regulation of protein localization to nucleus. Each is linked with GRIK1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRIK1-to-partner and partner-to-GRIK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ear morphogenesis grouped by GRIK1-low versus GRIK1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIK1→partner) and Y-score (partner→GRIK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Ear morphogenesis →	-0.038	-0.018	.005	.009	3	4
UPPER_AERODIGESTIVE_TRACT	Muscle adaptation →	-0.095	-0.018	.006	.009	3	4
BLOOD_Myeloma	Regulation of protein localization to nucleus →	+0.043	+0.034	.004	<.001	2	5
LARGE_INTESTINE	Nucleosome organization →	+0.073	+0.012	.001	.003	3	4
URINARY_TRACT	Regulation of presynaptic cytosolic calcium ion concentration →	-0.542	-0.025	<.001	.002	3	4
URINARY_TRACT	Organic hydroxy compound transport →	-0.067	-0.037	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 527 associations by consensus.

Ear morphogenesis by GRIK1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →