Across TCGA pan-cancer cohorts, GRID2IP Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GRID2IP data layer compared with 21 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GRID2IP Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated GRID2IP expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, READ, and ACC are the cancer types where GRID2IP Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	1.000	0.627	.004	30	view →
READ	OS	Median	All	0.281	0.823	<.001	9	view →
ACC	DFS	Median	All	0.088	0.476	.022	9	view →
ESCA	DFS	Median	All	0.213	0.538	.037	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: GRID2IP tumor-vs-normal RNA expression · all GRID2IP data types