Across TCGA patient cohorts, GRID2IP mutation is significantly associated with the RNA expression of many other genes, with 3,131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRID2IP-associated genes across cancer lineages are GAMTP2, OR5K4, and CLEC6A. Each is linked with GRID2IP in more than 2 cancer types. Because this analysis shows association rather than direction, both GRID2IP-to-partner and partner-to-GRID2IP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRID2IP→partner) and Y-score (partner→GRID2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	GAMTP2 →	+0.065	+5.091	<.001	.003	3	3
ACC	OR5K4 →	+0.040	+5.266	<.001	.001	3	2
UCEC	CLEC6A →	+0.150	+1.914	.002	<.001	3	2
ACC	SNORA84 →	+0.616	+4.212	<.001	.007	3	2
UCEC	BAG3 →	+0.676	+2.169	<.001	<.001	3	2
UCEC	C18orf25 →	+0.331	+1.654	.007	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,131 associations by consensus.

Exploration

GRID2IP survival (RNA) · tumor vs normal (RNA) · all GRID2IP data types