GRID2IP

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GRID2IP mutation is significantly associated with the RNA expression of many other genes, with 492 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GRID2IP-associated genes across cancer lineages are C1QBP, RPS12, and MRPL19. Each is linked with GRID2IP in more than 1 cancer types. Because this analysis shows association rather than direction, both GRID2IP-to-partner and partner-to-GRID2IP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRID2IP→partner) and Y-score (partner→GRID2IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEC1QBP →+0.614+2.129.002.00732
LARGE_INTESTINERPS12 →+0.462+3.321.004.00332
LARGE_INTESTINEMRPL19 →+0.558+3.850.001<.00132
LARGE_INTESTINEPRKG2 →-0.545-3.395.009.00132
LARGE_INTESTINECWC22 →+0.368+2.829.007<.00132
LARGE_INTESTINEFPGT →+0.550+3.523<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 492 associations by consensus.

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