GRID1

Across TCGA patient cohorts, GRID1 mutation is significantly associated with the RNA expression of many other genes, with 4,914 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GRID1-associated genes across cancer lineages are MYO19, NAPG, and RSPO4. Each is linked with GRID1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRID1-to-partner and partner-to-GRID1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYO19 grouped by GRID1-low versus GRID1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRID1→partner) and Y-score (partner→GRID1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYO19 →	+0.425	+2.588	<.001	<.001	3	4
COAD	NAPG →	+0.360	+1.736	.003	.007	3	4
UCEC	RSPO4 →	-1.000	-1.613	<.001	<.001	3	4
UCEC	BBC3 →	+0.461	+1.823	<.001	<.001	3	4
UCEC	UBE2S →	+0.578	+1.501	<.001	<.001	3	4
LUAD	NCAPG →	+0.815	+2.114	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,914 associations by consensus.

MYO19 by GRID1 expression — UCEC

Explore this box plot interactively →