GRIA3

Across TCGA cell cohorts, GRIA3 mutation is significantly associated with the RNA expression of many other genes, with 579 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GRIA3-associated genes across cancer lineages are TRMT10A, ZNF624, and MAGEB4. Each is linked with GRIA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRIA3-to-partner and partner-to-GRIA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRMT10A grouped by GRIA3-low versus GRIA3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIA3→partner) and Y-score (partner→GRIA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRMT10A →	+0.623	+3.169	.002	.009	3	2
LARGE_INTESTINE	ZNF624 →	+0.527	+3.502	<.001	.001	3	2
SKIN	MAGEB4 →	+0.008	+4.437	<.001	.004	3	1
SKIN	MDFIC2 →	+0.101	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	EIF3L →	+0.606	+3.257	<.001	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.717	+3.160	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 579 associations by consensus.

TRMT10A by GRIA3 expression — LARGE_INTESTINE

Explore this box plot interactively →