GRIA2

Across TCGA patient cohorts, GRIA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,000 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIA2-associated proteins across cancer lineages are HDGFL3, IVNS1ABP, and CRIP2. Each is linked with GRIA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRIA2-to-partner and partner-to-GRIA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIA2 versus HDGFL3 in BRCA, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIA2→partner) and Y-score (partner→GRIA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL3 →	+0.781	+2.027	<.001	<.001	3	5
UCEC	IVNS1ABP →	-0.571	-2.456	<.001	<.001	3	5
BRCA	CRIP2 →	+0.642	+2.210	<.001	<.001	3	5
BRCA	CASKIN1_S787 →	+1.219	+1.713	<.001	<.001	3	5
UCEC	THSD4 →	+0.875	+1.563	<.001	<.001	3	5
GBM	PURA →	+0.290	+1.351	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,000 associations by consensus.

GRIA2 vs HDGFL3 — BRCA

Explore this scatter interactively →