GRHPR

Across TCGA cell cohorts, GRHPR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,156 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GRHPR-associated GO terms across cancer lineages are sno(s)RNA catabolic process, Protoporphyrinogen IX metabolic process, and Heme B biosynthetic process. Each is linked with GRHPR in more than 8 cancer types. Because this analysis shows association rather than direction, both GRHPR-to-partner and partner-to-GRHPR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, sno(s)RNA catabolic process grouped by GRHPR-low versus GRHPR-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRHPR→partner) and Y-score (partner→GRHPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	sno(s)RNA catabolic process →	+0.154	+1.084	.002	.002	3	9
URINARY_TRACT	Protoporphyrinogen IX metabolic process →	+0.130	+0.975	.004	.003	3	8
URINARY_TRACT	Heme B biosynthetic process →	+0.130	+0.975	.004	.003	3	8
BONE	Regulation of aggrephagy →	+0.131	+0.449	.002	.002	3	8
LUNG_NSCLC_LUSC	CUT catabolic process →	+0.115	+0.745	<.001	.001	3	7
SOFT_TISSUE	Positive regulation of aggrephagy →	+0.141	+0.836	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,156 associations by consensus.

sno(s)RNA catabolic process by GRHPR expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →