GRHL3

Across TCGA patient cohorts, GRHL3 RNA expression is significantly associated with the RNA expression of many other genes, with 16,667 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible GRHL3-associated genes across cancer lineages are GRHL3-AS1, OVOL1, and IFNLR1. Each is linked with GRHL3 in more than 29 cancer types. Because this analysis shows association rather than direction, both GRHL3-to-partner and partner-to-GRHL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRHL3 versus GRHL3-AS1 in ESCA, with a Pearson correlation of 0.61.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRHL3→partner) and Y-score (partner→GRHL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	GRHL3-AS1 →	+0.698	+2.201	<.001	<.001	3	30
TGCT	OVOL1 →	+2.096	+1.500	<.001	<.001	3	25
CHOL	IFNLR1 →	+1.392	+0.938	<.001	.004	1	27
TGCT	CAPN1 →	+0.965	+1.304	<.001	<.001	3	25
UCS	CCDC120 →	+1.379	+1.342	<.001	<.001	2	25
BLCA	STPG1 →	+0.698	+1.944	<.001	<.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,667 associations by consensus.

GRHL3 vs GRHL3-AS1 — ESCA

Explore this scatter interactively →