GRHL3

Across TCGA patient cohorts, GRHL3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,844 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GRHL3-associated genes across cancer lineages are LYPD3, TTC9, and ZNF185. Each is linked with GRHL3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GRHL3-to-partner and partner-to-GRHL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRHL3 versus LYPD3 in UCEC, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRHL3→partner) and Y-score (partner→GRHL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LYPD3 →	+2.584	+1.534	<.001	.003	3	3
UCEC	TTC9 →	+1.067	+1.096	.002	.004	3	3
LSCC	ZNF185 →	+1.223	+1.673	<.001	<.001	3	3
LSCC	FUT3 →	+1.812	+1.414	<.001	<.001	3	3
UCEC	CRYBG2 →	+1.410	+1.250	<.001	.006	3	3
LSCC	GJA3 →	+0.749	+0.850	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,844 associations by consensus.

GRHL3 vs LYPD3 — UCEC

Explore this scatter interactively →