GREM2

Across TCGA patient cohorts, GREM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,981 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GREM2-associated proteins across cancer lineages are CNN1, OLFML3, and CAVIN3. Each is linked with GREM2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GREM2-to-partner and partner-to-GREM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GREM2 versus CNN1 in BRCA, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GREM2→partner) and Y-score (partner→GREM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CNN1 →	+1.186	+0.924	<.001	<.001	3	8
BRCA	OLFML3 →	+1.086	+1.018	<.001	<.001	3	8
BRCA	CAVIN3 →	+0.908	+1.084	<.001	<.001	3	7
LSCC	CLPX →	-0.331	-0.367	<.001	<.001	3	7
COAD	DENND2B →	+0.460	+1.052	<.001	<.001	3	7
OV	DIP2C →	+0.407	+0.517	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,981 associations by consensus.

GREM2 vs CNN1 — BRCA

Explore this scatter interactively →